{"product_id":"skin-hair-analysis-products-c-k-scientific-products-probes-invitro-tewameter-vt-310-probe-perfectly-suited-for-tewl-measurements-on-franz-cells","title":"Invitro Tewameter® VT 310 - Probe Perfectly Suited for TEWL-Measurements on Franz Cells","description":"\u003cdiv class=\"uk-grid-margin uk-grid uk-grid-stack\"\u003e \u003cdiv class=\"uk-width-1-1@m uk-first-column\"\u003e \u003ch1 class=\"uk-h1 uk-text-primary\"\u003eInvitro Tewameter® VT 310\u003c\/h1\u003e \u003c\/div\u003e \u003c\/div\u003e \u003cdiv class=\"uk-grid-margin uk-grid\"\u003e \u003cdiv class=\"uk-width-expand@m uk-first-column\"\u003e \u003cdiv class=\"uk-margin uk-margin-remove-bottom uk-text-center\"\u003e \u003cdiv class=\"uk-child-width-1-1 uk-child-width-1-1@m uk-grid uk-grid-stack\"\u003e \u003cdiv class=\"uk-first-column\"\u003e \u003cdiv class=\"el-item uk-box-shadow-medium uk-inline-clip uk-transition-toggle\"\u003e \u003cdiv class=\"uk-position-bottom-center\"\u003e \u003cdiv class=\"uk-overlay uk-padding-small uk-transition-fade uk-tile-default\"\u003e \u003ch3 class=\"el-title uk-margin uk-h6\"\u003eProbe perfectly suited for TEWL-measurements on Franz cells\u003c\/h3\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003cdiv class=\"uk-width-3-4@m\"\u003e \u003ch2 class=\"uk-margin-remove-top uk-h3\"\u003eProbe Perfectly Suited for TEWL-Measurements on Franz Cells\u003c\/h2\u003e \u003cdiv class=\"uk-margin\"\u003e \u003cp\u003eWith the Invitro Tewameter\u003cspan\u003e®\u003c\/span\u003e VT 310 a probe for the TEWL measurement is available, which offers all benefits of the Tewameter\u003cspan\u003e®\u003c\/span\u003e and is \u003cspan\u003eperfectly suited to sit on a Franz cell\u003c\/span\u003e.\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cdiv class=\"uk-margin-small\"\u003e \u003cdiv class=\"uk-child-width-expand uk-grid\"\u003e \u003ch3 class=\"el-title uk-margin\" style=\"display: inline !important;\"\u003eMeasuring with the Invitro Tewameter®\u003c\/h3\u003e \u003cdiv class=\"el-content uk-margin\"\u003e \u003cp\u003e\u003ca title=\"Invitro Tewameter® inside view\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/VT-probe.jpg?v=1723223608\" target=\"_blank\" data-wk-lightbox=\"on\" data-uk-lightbox=\"on\"\u003e\u003cimg title=\"Invitro Tewameter® inside view\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/VT-probe.jpg?v=1723223608\" alt=\"VT probe\" width=\"300\" height=\"146\"\u003e\u003c\/a\u003e\u003c\/p\u003e \u003cp\u003eThe probe Tewameter® VT 310 emulates completely the upper part (donor chamber) of a Franz cell (standard is 15 mm Ø, other sizes on request). Thus the probes sits exactly on the membrane of the Franz cell as it would sit on skin directly without needing further adapters. The measured TEWL-value is expressed in g\/h\/m², the worldwide acknowledged absolute measuring value for skin.\u003c\/p\u003e \u003cp\u003eNo other probe offers this possibility.\u003c\/p\u003e \u003cp\u003e\u003cimg title=\"probe with centerpiece on Franz cell\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/VT-with-centerpiece.jpg?v=1723223614\" alt=\"VT with centerpiece\" width=\"220\" height=\"236\"\u003e\u003c\/p\u003e \u003cp\u003eIf needed, the probe can also be used on a centerpiece of high quality Teflon, which fits exactly on the probe and the receptor chamber of the Franz cell without further fixing adapters. The thus measured TEWL has to be regarded relatively (no longer absolute figures as the distance between probe and membrane is changed).\u003c\/p\u003e \u003cp\u003eIn vitro TEWL measurements have a variety of different applications:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eInexpensive pre-screening before in vivo tests (no ethic commission, no expensive volunteers)\u003c\/li\u003e \u003cli\u003eOnly way to study skin permeability and dermal absorption necessary for safety and efficacy testing\u003c\/li\u003e \u003cli\u003eIn vitro tests and procedures to minimize the use of animals in tests are established in several worldwide acknowledged guidelines: e.g. ECVAM (European Centre for the Validation of Alternatives to Animal Testing), OECD (Organisation for Economic Co-operation and Development) or REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals)\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e \u003c\/p\u003e \u003ch3 class=\"el-title uk-margin\"\u003eAdantages of the Probe\u003c\/h3\u003e \u003cdiv class=\"el-content uk-margin\"\u003e \u003cul\u003e \u003cli\u003eThe probe offers all advantages of the “open chamber” measurement of the Tewameter\u003cspan\u003e®\u003c\/span\u003e, the worldwide most used TEWL-measuring device (even in space, the probe had been used for measurements on the ISS). Hundreds of publications performed with the probe prove this fact.\u003c\/li\u003e \u003cli\u003eThe Invitro Tewameter\u003cspan\u003e®\u003c\/span\u003e probe can replace the donor chamber of a Franz cell completely. \u003cspan\u003eThus it sits perfectly on the membrane, fully comparable to in vivo measurements.\u003c\/span\u003e The results are expressed in absolute figures (\u003cspan\u003eTEWL = g\/h\/m²\u003c\/span\u003e).\u003c\/li\u003e \u003cli\u003eNo further inconvenient adapters are needed.\u003c\/li\u003e \u003cli\u003eIf preparations are applied to the membrane during the measurement, a special centerpiece emulating the donor chamber made out of high quality, material-resistent Teflon can be put between probe and membrane. The probe fits exactly to the centerpiece and further adapters are not needed.\u003c\/li\u003e \u003cli\u003eThe standard probe fits to a Franz cell of 15 mm Ø. Other sizes between 10 - 20 mm Ø can be custom made (smaller or larger sizes on request).\u003c\/li\u003e \u003cli\u003e\u003cspan\u003eUp to 10 probes can measure simultaneously.\u003c\/span\u003e\u003c\/li\u003e \u003cli\u003e\u003cspan\u003eContinuous measurements over very long time periods are possible\u003c\/span\u003e\u003c\/li\u003e \u003cli\u003eDuring the measurement all TEWL values, averages and the standard deviations as well as the information on temperature and relative humidity of the two sensor pairs in the probe can be recorded and displayed.\u003c\/li\u003e \u003cli\u003eWith the open chamber measurement even higher water loss values can be detected accurately as no water is collected inside the probe.\u003c\/li\u003e \u003cli\u003e\u003cspan\u003eAccuracy of the probe can be checked anytime quickly.\u003c\/span\u003e\u003c\/li\u003e \u003cli\u003eAs the probe is very light and convenient, it may also be considered for other applications (e.g. fixing the probe to the skin with double sided sticking rings for long-term measurements, measurements under movement, etc.).\u003c\/li\u003e \u003cli\u003eThe Invitro Tewameter\u003cspan\u003e®\u003c\/span\u003e VT 310 can be connected to the MPA-systems (please see details in Basic Probe Systems). Please ask for package prices for several Invitro Tewameter\u003cspan\u003e®\u003c\/span\u003e-probes with basic unit.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cspan\u003e\u003ca title=\"Tewitro® - TEWL measurement on up to 24 cultured skin wells simultaneously\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/Tewitro01.jpg?v=1723220444\" target=\"_blank\" data-wk-lightbox=\"on\" data-uk-lightbox=\"on\"\u003e\u003cimg title=\"Tewitro® - TEWL measurement on up to 24 cultured skin wells simultaneously\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/Tewitro01.jpg?v=1723220444\" alt=\"Tewitro01\" width=\"250\" height=\"237\"\u003e\u003c\/a\u003e    \u003c\/span\u003e\u003cimg title=\"Ideen für besondere Anwendungen auf der Haut\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/VT-on-skin.jpg?v=1723223619\" alt=\"VT on skin\" width=\"187\" height=\"245\"\u003e\u003c\/p\u003e \u003cp\u003eOther related probes available:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eTewitro\u003cspan\u003e®\u003c\/span\u003e TW 24: TEWL measurement on up to 24 cultured skin wells simultaneously\u003c\/li\u003e \u003cli\u003eTewameter\u003cspan\u003e®\u003c\/span\u003e TM Hex: the ultimative TEWL measurement with one head\u003c\/li\u003e \u003cli\u003eTewameter\u003cspan\u003e®\u003c\/span\u003e TM Nano: ideal tool for small or difficult to reach skin sites (e.g. nail, lips, scalp with hair)\u003c\/li\u003e \u003cli\u003eTewameter\u003cspan\u003e®\u003c\/span\u003e Triple TM 330T: TEWL measurement probe with three flexible measurement heads to measure either on a large surface or on three different surfaces simultaneously\u003c\/li\u003e \u003c\/ul\u003e \u003c\/div\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003chr\u003e \u003cdiv class=\"uk-margin-small uk-margin-remove-top uk-text-center\"\u003e\u003ca class=\"el-content\" title=\"Download brochure\" href=\"https:\/\/www.courage-khazaka.de\/images\/Downloads\/Brochures\/Wissenschaftlich\/Brochure_Tewameter_Nano_Triple_In-vitro.pdf\" target=\"_blank\"\u003e \u003cspan class=\"uk-text-middle\"\u003eDownload brochure\u003c\/span\u003e\u003c\/a\u003e\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"Courage + Khazaka electronic GmbH","offers":[{"title":"Default Title","offer_id":45717529460971,"sku":"CK_invitro","price":0.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0704\/1427\/0699\/files\/VT-on-membran-close-up__22755.1677760804.1000.1200.jpg?v=1723223602","url":"https:\/\/medisa.com.au\/en-nz\/products\/skin-hair-analysis-products-c-k-scientific-products-probes-invitro-tewameter-vt-310-probe-perfectly-suited-for-tewl-measurements-on-franz-cells","provider":"Medisa","version":"1.0","type":"link"}