How to Clean ENFit Connectors with an EnClean Cleaning Brush
A Practical Guide to Cleaning ENFit Connectors
Food, enteral formula or medication can leave residue inside an ENFit connection, including areas that are difficult to reach from the outside. This guide looks at where residue can remain, how the EnClean brush reaches these areas, and the practical differences between single-use and reusable options.

What is an EnClean Cleaning Brush?
EnClean is designed specifically for cleaning compatible ENFit enteral feeding connectors. The bristles are inserted into the connection and rotated so they can reach the internal surfaces and bottom of the connector.
This becomes relevant when food, enteral formula or medication leaves residue inside the connection. Instead of cleaning only the visible outer surface, the brush reaches into the part of the connector where residue may remain.
In simple terms: EnClean is a cleaning tool for the ENFit connector itself. It is not a general-purpose brush for cleaning all enteral feeding equipment.
Why can ENFit connectors be difficult to clean?
ENFit connectors are used to connect compatible enteral feeding devices and accessories. The internal shape of the connection includes recessed surfaces that are less accessible than the outside of the connector.
During feeding or medication administration, residue can remain within these areas. Effective connector cleaning therefore needs to reach inside the connection rather than stopping at the visible external surface.
Enteral formula
Formula can leave material within the connection after use.
Medication
Medication given through compatible enteral equipment can also leave residue around the connector.
Recessed areas
Internal threads and the bottom of the connection are less accessible than the external surface.

How does the EnClean brush reach inside the connector?
The cleaning action is mechanical. The bristles are wetted with clean water and inserted into the compatible ENFit connector until they reach the bottom. Rotating the brush then brings the bristles into contact with the internal surfaces of the connection.
As residue is collected by the brush, the bristles are rinsed in clean water. Cleaning and rinsing are repeated until the connector is clean.
Inside the connector
EnClean is intended to reach the internal area and bottom of a compatible ENFit connection rather than only the visible exterior.
Wet, insert, rotate and rinse
The brush uses direct physical contact with the internal connector surfaces to support removal of residue.
How do you clean an ENFit connector with EnClean?
The manufacturer's instructions describe a short cleaning sequence. The steps below summarise the connector-cleaning part of the process; always follow the complete Instructions for Use supplied with the specific EnClean product.
Wet the bristles
Wet the cleaning bristles with clean water.
Insert the brush
Insert the wet bristles into the compatible ENFit connector until they reach the bottom.
Rotate inside the connector
Rotate the brush to clean the internal area and bottom of the ENFit connection.
Rinse the bristles
Rinse the bristles in clean water during cleaning to remove residue collected by the brush.
Repeat as needed
Continue the rotate-and-rinse process until the connector is clean.

Single-use or reusable: what is the difference?
Both EnClean formats are made for the same core task: cleaning compatible ENFit connectors. The important difference is how the brush is handled after use.
EnClean Single-Use Brush
The single-use version is used for connector cleaning and then discarded.
- Designed for compatible ENFit connectors
- Used once
- Discard after use
- Do not reuse
- Available from Medisa in a box of 100
EnClean Reusable Brush
The reusable version can be used again by the same patient when it is cleaned and maintained according to its Instructions for Use.
- Designed for compatible ENFit connectors
- Same-patient reuse only
- Clean after every use
- Designed for reuse for up to 30 days
- Available from Medisa individually and in a box of 10
What happens after using the reusable EnClean brush?
Once the connector has been cleaned, the manufacturer's instructions direct the user to rinse the reusable brush bristles and brush cap with antiseptic mouthwash, replace the cap and leave the brush standing upright to dry.
The brush can then be used again by the same patient. It should be cleaned after every use and is designed for reuse for up to 30 days.

Which EnClean format should you consider?
The main practical difference is simple: the single-use version is discarded after use, while the reusable version needs to stay with the same patient and be maintained according to its Instructions for Use.
Where does EnClean fit into enteral feeding equipment?
ENFit connections are used across compatible enteral feeding products such as syringes, feeding tubes, extension sets and related accessories. EnClean has a much narrower role within that system: cleaning the connector itself.
If you want a broader explanation of the connector first, read ENFit Explained .
For information about compatible syringe formats, see How to Choose the Right ENFit Syringe for Enteral Feeding . You can also browse Feeding Sets & Accessories available from Medisa.
View EnClean Cleaning Brushes
Medisa supplies EnClean cleaning brushes for compatible ENFit connectors in single-use and reusable formats. Visit the product page to compare current pack options, pricing and availability.
View EnClean Cleaning BrushesContinue exploring ENFit
Questions about EnClean and ENFit connector cleaning
The questions below cover the main practical differences between the EnClean formats and the points that matter when using or purchasing the product.
Why can residue remain inside an ENFit connector?
Food, enteral formula or medication can come into contact with the internal surfaces of the connection during use. Because some parts of an ENFit connector are recessed, residue may remain around the internal threads or bottom rather than only on the visible external surface.
How do I clean an ENFit connector with an EnClean brush?
The manufacturer's cleaning sequence involves wetting the bristles with clean water, inserting them into the compatible ENFit connector until they reach the bottom, rotating the brush, rinsing residue from the bristles and repeating the process until the connector is clean. Always follow the complete Instructions for Use supplied with the specific EnClean product.
What is the difference between single-use and reusable EnClean brushes?
Both are designed to clean compatible ENFit connectors. The single-use brush is discarded after use. The reusable EnClean can be used again by the same patient and has specific cleaning, drying and storage instructions between uses.
Can a reusable EnClean brush be used for more than one patient?
No. The reusable EnClean brush is intended for reuse by the same patient only and should not be shared between patients.
How long can the reusable EnClean brush be used?
The reusable EnClean brush is designed for reuse for up to 30 days when it is used and maintained according to the manufacturer's Instructions for Use. It should be cleaned after every use and discarded if damaged.
How should the reusable EnClean brush be cleaned and stored after use?
After cleaning the ENFit connector, the manufacturer's instructions direct the user to rinse the brush bristles and brush cap with antiseptic mouthwash, replace the cap and leave the brush upright to dry. It can then be used again by the same patient.
Which EnClean pack sizes does Medisa supply?
Medisa currently lists the reusable EnClean brush individually and in a box of 10, while the single-use version is listed in a box of 100. For procurement or repeat-order requirements, check the product page for current pricing, availability and pack options.